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Wegovy weight loss program

Take control of your weight with Wegovy

4.7 37,000+ reviews
Supportive healthcare professional
  • Personalised plan, reviewed by clinicians
  • Patients have seen up to 20% body weight loss
  • Ongoing support at every step of treatment
  • Personalised plan, reviewed by clinicians
  • Patients have seen up to 20% body weight loss
  • Ongoing support at every step of treatment

Starting dose

Indicative starting dose for reference. Your clinician will determine the appropriate dose based on your medical assessment. Treatment may not be suitable for everyone.

UK-registered pharmacy
Clinician-led prescribing
Speedy, discreet delivery

About Wegovy

Wegovy (semaglutide) is a once-weekly injection that helps reduce appetite and regulate blood sugar. It mimics the natural hormone GLP-1 to slow digestion, improve insulin release, and make you feel fuller for longer.

Wegovy Summary

A quick overview of key details.

Summary
PriceFrom £99 / Month
How it worksSuppresses appetite
EffectivenessUp to 20% body weight loss
EligibilityBMI over 30, or over 27 with a weight-related condition
Side effectsCommon side effects include nausea, diarrhoea, constipation
DosageStarting at 0.25mg once weekly. Maximum dosage of 2.4mg once weekly.
What is Wegovy?

Wegovy is a clinically proven, UK licensed weight loss treatment. Clinical trials have shown it can help achieve up to 20% body weight loss. It is a GLP-1 weight loss medication prescribed for people with a body mass index (BMI) over 30. It can also be prescribed for patients with a BMI of 27+ and a weight-related medical condition. The active ingredient semaglutide is manufactured by Novo Nordisk. It is the same active ingredient found in Ozempic, but Wegovy is specifically licensed for weight management.

How it works

Wegovy works by mimicking the action of GLP-1, a natural hormone produced in the gut after eating. This hormone plays a key role in appetite regulation. Its main effects are: It helps regulate appetite, making it easier to eat less It slows stomach emptying, making you feel fuller for longer Both actions lead to eating fewer calories, which results in weight loss.

Is it for me?

Wegovy should only be used to support weight loss if lifestyle changes like regular exercise and diet haven't been successful. Other GLP-1 medications are also available in the UK, including Saxenda, Mounjaro and Ozempic. Wegovy can be used for patients who have a BMI of over 30, or in patients with a BMI over 27, and other risk factors such as: Type 2 diabetes High cholesterol Obstructive sleep apnoea High blood pressure

How effective is Wegovy?

Clinical trials show an average weight loss of 20% when using the 7.2mg dose combined with diet and exercise.

Dosage

The dosage table below outlines the recommended titration for Wegovy when used for weight loss.

WeeksDoseNotes
1-40.25 mg once weeklyInitial dose for titration
5-80.5 mg once weeklyAssess tolerance before increase
9-121 mg once weeklyAssess tolerance before increase
13-161.7 mg once weeklyMonitor for efficacy and tolerability
17 onwards2.4 mg once weeklyMaintenance dose if well tolerated
Side effects of Wegovy

The most common side effects with Wegovy affect the digestive system. These can include things like nausea, vomiting, diarrhoea and constipation. Most patients should see these effects subside after a few days. Other common side effects include: Feeling weak or tired Dizziness Headache Injection site reactions

What our patients tell us

People come to us for different reasons, but most are looking for a safe, supported way to manage their weight.

20 %

of body weight lost (in studies) *

9 in 10

reported health improvements

7 in 10

reported increased confidence

* Based on clinical study results and patient-reported outcomes. Individual results vary.

Read our GLP-1 weight loss survey and key insights

What our expert says

Wegovy has been a game-changer for many patients struggling with weight management. By helping to control hunger and cravings, it allows people to make sustainable changes to their eating habits and focus on their overall health journey.

Abdal Alvi, Chief Clinical Officer

Abdal Alvi

Chief Clinical Officer

How to get started

Taking the first steps to feeling healthier overall

Complete a simple assessment

Answer questions about your health, lifestyle, and goals.

Your assessment is reviewed by a clinician

A UK-registered prescriber carefully reviews your assessment to ensure treatment is safe and suitable for you.

Receive discreet delivery

Your medication is dispensed by our registered pharmacy and delivered directly to your door in plain packaging.

Stay supported

Schedule reviews with our specialist teams to monitor your progress and provide support throughout your journey.

Wegovy Titration Guide

Your clinician will guide your dose increases. This schedule shows the typical 4-week steps for Wegovy.

This table shows the Wegovy titration schedule across 20 weeks, organized by dosage levels from 0.25mg to 2.4mg. Each dosage level spans 4 weeks, with instructions for ordering and completing each pen.

0.25mg
Week 1
Week 2
Week 3 Order next pen
Week 4 Pen finished
0.5mg
Week 5
Week 6
Week 7 Order next pen
Week 8 Pen finished
1mg
Week 9
Week 10
Week 11 Order next pen
Week 12 Pen finished
1.7mg
Week 13
Week 14
Week 15 Order next pen
Week 16 Pen finished
2.4mg
Week 17
Week 18
Week 19 Order next pen
Week 20 Pen finished

Our expert team

Our committed clinical team, consisting of expert doctors, pharmacists, dietitians, and health coaches, is dedicated to supporting you at every stage of your health journey. Join over 3,000,000 UK patients who trust Simple Online Pharmacy with their health.

What our patients say

4.7 out of 5 stars from 37,000+ reviews 4.7 out of 5 (37,000+ reviews)
See all reviews

GB · 5 reviews

5 out of 5 stars Verified

Quick and simple

Filled out a reasonably in-depth questionnaire, uploaded images and then prescription was dispatched for next day delivery within the hour. Very detailed how to use guide, couldn't be simpler.

GB · 1 review

5 out of 5 stars Verified

Great company to deal with...

This company is easy and reliable to deal with. They have your best interests in mind and are vigilant about checking in with you about your health which indicates that they actually care.

GB · 40 reviews

5 out of 5 stars Verified

Online Doctor - 5 stars

I have been using SOL pharmacy for sometime now and I can honestly say the support is available 24/7 for any questions that may arise. The use of the online doctor was easy to access and provided clear direction swiftly.

General information

Answers to common questions about Wegovy.

What is Wegovy?

Wegovy (semaglutide) is a GLP-1 agonist medication licensed in the UK for weight management in adults with obesity (BMI ≥30) or overweight (BMI ≥27) with weight-related health conditions.

How does Wegovy work?

It mimics the GLP-1 hormone to slow digestion, reduce appetite, and increase satiety, helping lower calorie intake and support sustained weight loss.

Is Wegovy safe?

Yes, when prescribed appropriately. It is MHRA-approved but is contraindicated for individuals with a history of medullary thyroid carcinoma, pancreatitis, or those who are pregnant.

How many Wegovy pens are in a box?

Each box of Wegovy contains one pre-filled pen, which provides four once-weekly doses. One pen lasts four weeks of treatment.

Is Wegovy the same as Ozempic?

Both contain semaglutide, but Wegovy is approved for weight loss at higher doses (up to 2.4mg weekly), while Ozempic is licensed for type 2 diabetes at lower doses.

Usage & dosage

How Wegovy is taken and how dosing progresses.

How is Wegovy administered?

It is administered as a once-weekly subcutaneous injection in the abdomen, thigh, or upper arm.

What is the dosage schedule?

Begin at 0.25mg per week for 4 weeks, then gradually increase every 4 weeks to a maintenance dose of 2.4mg per week. Patients may also choose to increase their dose further, to 7.2mg per week (given as three 2.4mg doses).

What if I miss a dose?

Take the missed dose within 5 days. If more than 5 days pass, skip the missed dose and resume your regular schedule.

Can I adjust the dose myself?

No. You must follow the prescribed titration schedule to minimise side effects.

How many doses of Wegovy are in one pen?

Each Wegovy pre-filled pen contains four once-weekly doses and lasts four weeks. Pens are colour-coded to match your current stage in the titration schedule.

Effectiveness & results

What to expect over time with Wegovy.

How much weight can I lose with Wegovy?

Clinical trials show an average weight loss of 20% when using the 7.2mg dose combined with diet and exercise.

How long until I see results?

Most users notice appetite suppression within days, while significant weight loss typically begins after 8–12 weeks.

Will I regain weight if I stop Wegovy?

Weight regain is possible without ongoing lifestyle changes such as healthier eating and increased physical activity. Wegovy is intended for long-term use under medical supervision.

Does Wegovy improve obesity-related conditions?

Yes, it can reduce risks of heart disease, type 2 diabetes, and improve overall metabolic health.

Side effects & safety

Common side effects and key safety considerations.

What are common side effects?

Common side effects include nausea, vomiting, diarrhoea, constipation, and abdominal pain. These often resolve as the body adjusts.

Can Wegovy cause thyroid cancer?

Animal studies have linked semaglutide to thyroid tumours. Wegovy should be avoided if you or any family members have a history of medullary thyroid carcinoma or MEN syndrome.

Is Wegovy safe during pregnancy or breastfeeding?

No. Wegovy is not recommended during pregnancy or breastfeeding. Discontinue use if planning pregnancy and use contraception while on treatment.

Interactions

Medication and lifestyle interactions to be aware of.

Does Wegovy interact with other medications?

Wegovy may increase the risk of hypoglycaemia if used with insulin or sulfonylureas. Additionally, oral contraceptives may be less effective—use backup contraception if necessary.

Can I drink alcohol with Wegovy?

Moderate alcohol consumption is generally acceptable when using Wegovy. However, excessive drinking may worsen gastrointestinal side effects. It is also worth noting that many alcoholic drinks are calorie-dense, which can hinder your ability to lose weight.

Storage

Storage guidance for Wegovy at home and while travelling.

How should I store Wegovy?

Unopened pens should be refrigerated at 2–8°C. Once opened, store Wegovy at room temperature (≤30°C) and use within 42 days.

Can I travel with Wegovy?

Yes. Keep unopened pens in a fridge (36–46°F / 2–8°C) and use a cool bag or insulated case with gel packs while travelling with Wegovy. Avoid heat or freezing. Once opened, a pen can be kept at room temperature (below 86°F / 30°C) for up to 30 days. Always carry pens in your hand luggage, not checked baggage.

Access & cost

Availability, access pathways, and pricing context.

Is Wegovy available on the NHS?

Wegovy (semaglutide) is available on the NHS through specialist weight management services for eligible patients. It may be prescribed if you have weight-related health problems and a BMI of 35 or higher (or 32.5 or higher for people of Asian, Chinese, Middle Eastern, Black African or African-Caribbean origin). In some cases, it may be offered to those with a BMI between 30 and 34.9 (or 27.5 and 32.4 for the above groups) if additional clinical criteria are met. Wegovy has limited availability on the NHS and is primarily prescribed privately for weight loss.

Can I buy Wegovy online in the UK?

Yes. For example, Simple Online Pharmacy offers Wegovy after a clinician reviews your eligibility through an online consultation.

How much does Wegovy cost?

Prices typically range from £99 to £329 per month, depending on the dose and prescription length.

What are alternatives to Wegovy?

Alternatives include Saxenda (liraglutide), Orlistat, or Mounjaro (tirzepatide). Consult with your clinician to determine the best option for you.

Aamina Rafiq

Reviewed by

Aamina Rafiq

Clinical Pharmacist

This page has been reviewed by our clinical team to ensure it is clear, accurate, and up to date.

Last updated: 10 February 2026